Web25 de nov. de 2024 · Inside the cancer microenvironment, reduced O 2 concentration, termed as hypoxia, is a common phenotype and leads to cancer progression. However, little is known about how and when those HIF members are dysregulated in distinct cancers. Here, by integrating a full range of data of thousands of patients, we comprehensively … Web10 de nov. de 2024 · We found that HIF-1α is involved, along with the NLRP3 inflammasome, in promoting pyroptosis. Inhibition of HIF-1α may alleviate NLRP3/caspase-1-mediated pyroptosis, and thus reduce brain injury after stroke. We also established that inhibition of HIF-1α decreased apoptosis by reducing immune cell infiltration.
Trascrizione dei geni trascrizione genetica. Ricerca medica.
Web9 de out. de 2007 · Abstract. Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix-PAS domain transcription factor that is expressed in all metazoan organisms and is … WebIl fattore inducibile dell'ipossia (HIF) è stato originariamente identificato come un regolatore trascrizionale centrale delle risposte cellulari alla deprivazione di ossigeno. Tuttavia, la via di segnalazione HIF ora sembra, almeno nelle cellule mieloidi, essere un regolatore principale della funzione e della sopravvivenza delle cellule immunitarie. small business project software
IHF - Wikipedia
Webvon Hippel-Lindau (VHL) disease is a hereditary cancer syndrome that is characterized by the development of multiple vascular tumors and is caused by inactivation of the von … Web9 de out. de 2007 · Abstract. Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix-PAS domain transcription factor that is expressed in all metazoan organisms and is composed of HIF-1α and HIF-1β subunits. Under hypoxic conditions, HIF-1 regulates the transcription of hundreds of genes in a cell type–specific manner. The HIF-1α subunit is … WebLa terminologia fattore di crescita dell'endotelio vascolare (in inglese vascular endothelial growth factor, da cui la sigla VEGF) indica una specifica sottofamiglia di fattori di crescita … some is red