WebIt is described that the EMT-inducing transcriptional repressor ZEB1 promotes colorectal cancer cell metastasis and loss of cell polarity and shows that retention of Lgl2 expression is critical for the epithelial phenotype and that its loss might be involved in metastasis. Invasion and metastasis are the hallmarks of malignant tumor progression and the main cause of … WebChapter 6 EPITHELIAL-MESENCHYMAL TRANSITION IN COLORECTAL CANCER Otto Schmalhofer1, Simone Brabletz2 and Thomas Brabletz3 1Department of Visceral Surgery, University of Freiburg, Freiburg, 79106, Germany, e-mail: [email protected] 2Department of Visceral Surgery, University of Freiburg, Freiburg, 79106, …
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WebFalk Hlubek 1, Simone Spaderna 1, Otto Schmalhofer 1, Andreas Jung 1, Thomas Kirchner 1, Thomas Brabletz 1,* Show Less 1 Department of Pathology, University of Erlangen-Nürnberg, Krankenhausstr. 8-10, 91054 Erlangen , Germany WebOtto Schmalhofer & Simone Brabletz & Thomas Brabletz Published online: 20 January 2009 # Springer Science + Business Media, LLC 2009 Abstract The embryonic program ‘epithelial-mesenchymal transition’ (EMT) is activated during tumor invasion in disseminating cancer cells. Characteristic to these cells is a
WebMay 16, 2008 · Otto Schmalhofer. Otto Schmalhofer. Department of Visceral Surgery, University of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany. Search for more papers by this author. Elizabeth Vincan. Elizabeth Vincan. Department of Anatomy and Cell Biology, University of Melbourne, Cnr Grattan Street, Parkville, Victoria, 3010 Australia.
WebSep 1, 2006 · @article{Spaderna2006ATE, title={A transient, EMT-linked loss of basement membranes indicates metastasis and poor survival in colorectal cancer.}, … WebUlrike Burk, Jörg Schubert, Ulrich Wellner, Otto Schmalhofer, Elizabeth Vincan, Simone Spaderna, Thomas Brabletz ZEB1 directly suppresses transcription of microRNA‐200 family members miR‐141 and miR‐200c, which strongly activate epithelial differentiation in pancreatic, colorectal and breast cancer cells. EMBO Rep (2008) 9: 582-589 Esther …
WebJul 1, 2008 · Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S, Brabletz TA reciprocal repression between ZEB1 and members of the miR-200 family …
WebOtto Schmalhofer As seen in: Nature. Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a … healthy granola bar recipe homemadeWebNuclear β-catenin cooperates with transcriptional repressors of the E-cadherin gene to induce epithelial-mesenchymal transition and activates expression of target genes that drive malignant tumour progression. Colorectal carcinomas are characterized by a heterogeneous differentiation pattern. Cancer cells in central regions are epithelially-differentiated, … motorwayservices.ieWebOtto Schmalhofer Department of Visceral Surgery, University of Freiburg, Freiburg 79106, Germany, [email protected] B. Uzzan Departments of Pharmacology, APHP, hôpital Avicenne, Bobigny 93009, France Té Vuong Department of Radiation Oncology, Jewish General Hospital, McGill healthy granola bar recipe peanut butterWebOtto Schmalhofer (1891 - 1983) How do we create a person’s profile? We collect and match historical records that Ancestry users have contributed to their family trees to create each person’s profile. We encourage you to research and examine these records to determine their accuracy. ... healthy granola bars grocery storeWebJan 15, 2008 · , Otto Schmalhofer, Mandy Wahlbuhl, Arno Dimmler, Katja Bauer, Aneesa Sultan, Falk Hlubek, Andreas Jung, Dennis Strand, Andreas Eger, Thomas Kirchner, … healthy granola bar for kidsWebAccumulating data demonstrate that aberrant nuclear expression of beta-catenin can confere these two abilites also to tumor cells, and the unusual combination of EMT with stem cell competence might result in a migrating tumor stem cell, which drives tumor invasion and metastasis. Invasion by colorectal carcinomas is characterized by an epithelial … healthy granola bar recipe chewyWeb@MISC{Burk_embo, author = {Ulrike Burk and Jörg Schubert and Ulrich Wellner and Otto Schmalhofer and Elizabeth Vincan and Simone Spaderna}, title = {EMBO}, year = {}} … healthy granola bar recipe no bake