WebOct 1, 2003 · Triplicated α-globin genes appear to be ubiquitous and have been found in most populations ( 2 ). They result from misalignment and unequal crossover between the homologous X-, Y-, and Z-box segments of the α-globin … WebJan 31, 2024 · triplication Introduction The α-thalassemia is one of the most common inherited disorders worldwide [ 1 ]. It mainly occurs in tropical and subtropical regions, including southern China, with a high carrier rate of 11.31% and 17.55%, respectively, in Guangdong and Guangxi provinces [ 2, 3 ].
Alpha‐globin gene triplication and its effect in beta‐thalassemia
Web1. A redoubling. 2. A duplication or doubling, as of the sounds of the heart in certain morbid states or the presence of two instead of a normally single part. 3. A fold or duplicature. [L. reduplicatio, fr. re-, again, + duplico, to double, fr. duplex, two-fold] Farlex Partner Medical Dictionary © Farlex 2012 re·du·pli·ca·tion ( rē-dū'pli-kā'shŭn) WebNov 19, 2024 · While this triplication is not a pathogenic variant in itself, the combination of a triplication with certain pathogenic HBB variants may lead to a clinically significant phenotype due to the... give thanks ceramic pumpkin
A genome triplication associated with early diversification of the …
WebNov 27, 2012 · Overexpression of wild-type α-synuclein has also been identified as a cause of PD in families with heterozygous triplications or duplications of the region of chromosome 4 that comprises SNCA ... WebAlthough triplications are more rare, they have been observed previously in DYS19 (10) and DYS385 (11,12; Table 1). Tripli-cations at DYS385 can arise through a duplication of one of the already duplicated DYS385 alleles or a duplication of the entire Y-chromosome region containing both the “a” and “b” alleles. Of- WebApr 11, 2024 · Input filtering. The following flags allow you to exclude samples and/or variants from an analysis batch based on a variety of criteria. Two general notes: When a filter type can apply to either samples or variants, the sample-filter flag names start with 'keep'/'remove', and the variant-filter flag names start with 'extract'/'exclude'. Some of ... give thanks chords lyrics